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一例与心脏直视手术后输血相关的致命性西尼罗河病毒脑膜脑炎病例。

A case of fatal West Nile virus meningoencephalitis associated with receipt of blood transfusions after open heart surgery.

作者信息

Armstrong Wendy S, Bashour C Allen, Smedira Nicholas G, Heupler Frederick A, Hoeltge Gerald A, Mawhorter Steven D, Sudheendra Vijayendra, Gordon Steven M

机构信息

Department of Infectious Disease, Cleveland Clinic Foundation, Ohio 44195, USA.

出版信息

Ann Thorac Surg. 2003 Aug;76(2):605-7. doi: 10.1016/s0003-4975(03)00271-6.

DOI:10.1016/s0003-4975(03)00271-6
PMID:12902115
Abstract

First identified in the United States in 1999, West Nile virus caused approximately 3,500 infections in the late summer and fall of 2002. The virus is predominantly transmitted by mosquitoes, and the risk of infection through blood product transfusion is believed to be low. We present a case of West Nile virus encephalitis transmitted by red blood cell transfusion at the time of coronary artery bypass grafting that resulted in the patient's death. Individuals undergoing procedures with high blood product transfusion requirements, such as cardiac surgery or organ transplantation, may be at higher risk of this nosocomial infection during epidemics.

摘要

西尼罗河病毒于1999年在美国首次被发现,2002年夏末秋初导致了约3500例感染。该病毒主要通过蚊子传播,通过输血感染的风险被认为较低。我们报告了一例在冠状动脉搭桥手术时因输注红细胞而传播的西尼罗河病毒脑炎病例,该病例导致患者死亡。在疫情期间,接受心脏手术或器官移植等高输血需求手术的个体可能面临更高的这种医院感染风险。

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