Carlier A, Uroz S, Smadja B, Fray R, Latour X, Dessaux Y, Faure D
Institut des Sciences du Végétal, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France.
Appl Environ Microbiol. 2003 Aug;69(8):4989-93. doi: 10.1128/AEM.69.8.4989-4993.2003.
The Agrobacterium tumefaciens C58 genome contains three putative N-acyl homoserine lactone (acyl-HSL) hydrolases, which are closely related to the lactonase AiiA of Bacillus. When expressed in Escherichia coli, two of the putative acyl-HSL hydrolases, AttM and AiiB, conferred the ability to degrade acyl-HSLs on the host. In Erwinia strain 6276, the lactonases reduced the endogenous acyl-HSL level and the bacterial virulence in planta.
根癌农杆菌C58基因组包含三种假定的N-酰基高丝氨酸内酯(酰基-HSL)水解酶,它们与芽孢杆菌的内酯酶AiiA密切相关。当在大肠杆菌中表达时,两种假定的酰基-HSL水解酶AttM和AiiB赋予宿主降解酰基-HSL的能力。在欧文氏菌菌株6276中,内酯酶降低了植物体内的内源性酰基-HSL水平和细菌毒力。