Min Robert J, Khilnani Neil, Zimmet Steven E
Cornell Vascular, Weill Medical College of Cornell University, 416 East 55th Street, New York, New York 10022, USA.
J Vasc Interv Radiol. 2003 Aug;14(8):991-6. doi: 10.1097/01.rvi.0000082864.05622.e4.
To report long-term follow-up results of endovenous laser treatment for great saphenous vein (GSV) reflux caused by saphenofemoral junction (SFJ) incompetence.
Four hundred ninety-nine GSVs in 423 subjects with varicose veins were treated over a 3-year period with 810-nm diode laser energy delivered percutaneously into the GSV via a 600- micro m fiber. Tumescent anesthesia (100-200 mL of 0.2% lidocaine) was delivered perivenously under ultrasound (US) guidance. Patients were evaluated clinically and with duplex US at 1 week, 1 month, 3 months, 6 months, 1 year, and yearly thereafter to assess treatment efficacy and adverse reactions. Compression sclerotherapy was performed in nearly all patients at follow-up for treatment of associated tributary varicose veins and secondary telangiectasia.
Successful occlusion of the GSV, defined as absence of flow on color Doppler imaging, was noted in 490 of 499 GSVs (98.2%) after initial treatment. One hundred thirteen of 121 limbs (93.4%) followed for 2 years have remained closed, with the treated portions of the GSVs not visible on duplex imaging. Of note, all recurrences have occurred before 9 months, with the majority noted before 3 months. Bruising was noted in 24% of patients and tightness along the course of the treated vein was present in 90% of limbs. There have been no skin burns, paresthesias, or cases of deep vein thrombosis.
Long-term results available in 499 limbs treated with endovenous laser demonstrate a recurrence rate of less than 7% at 2-year follow-up. These results are comparable or superior to those reported for the other options available for treatment of GSV reflux, including surgery, US-guided sclerotherapy, and radiofrequency ablation. Endovenous laser appears to offer these benefits with lower rates of complication and avoidance of general anesthesia.
报告腔内激光治疗大隐静脉(GSV)因隐股静脉交界处(SFJ)功能不全所致反流的长期随访结果。
在3年期间,对423例静脉曲张患者的499条大隐静脉进行治疗,通过一根600微米的光纤经皮将810纳米二极管激光能量输送到大隐静脉内。在超声(US)引导下经静脉给予肿胀麻醉(100 - 200毫升0.2%利多卡因)。在1周、1个月、3个月、6个月、1年及此后每年对患者进行临床评估和双功超声检查,以评估治疗效果和不良反应。几乎所有患者在随访时均进行压迫硬化疗法,以治疗相关的属支静脉曲张和继发性毛细血管扩张。
初次治疗后,499条大隐静脉中有490条(98.2%)实现了成功闭塞,定义为彩色多普勒成像显示无血流。在随访2年的121条肢体中,有113条(93.4%)保持闭塞状态,大隐静脉的治疗部分在双功成像中不可见。值得注意的是,所有复发均发生在9个月之前,大多数发生在3个月之前。24%的患者出现瘀斑,90%的肢体在治疗静脉走行处有紧绷感。未发生皮肤烧伤、感觉异常或深静脉血栓形成病例。
对499条肢体进行腔内激光治疗的长期结果显示,在2年随访时复发率低于7%。这些结果与报道的其他治疗大隐静脉反流的方法(包括手术、超声引导下硬化疗法和射频消融)相当或更优。腔内激光似乎能以较低的并发症发生率和避免全身麻醉的方式提供这些益处。