Arterial hemostasis using the Duett sealing device.

Using a liquid procoagulant, the Duett sealing device employs a distinctly different mechanism than other available devices for attaining hemostasis after femoral arterial puncture. Approved for use with 5 to 9 Fr sheath sizes, the Duett incorporates the typical vascular sheath in the closure procedure. Moreover, the liquid procoagulant, containing a mixture of thrombin and collagen, provides instant hemostasis and does not leave foreign material in the artery or in the subcutaneous tissues. Several studies, including one comparing the Duett to standard manual compression (SEAL), have shown the safety of the device as well as decreased times to ambulation. In addition, time to hemostasis was significantly decreased in patients receiving anticoagulation or antiplatelet therapy. The Duett sealing device is simple to use, safe, effective and a viable alternative to other available devices and/or manual compression.