Hirota K, Hattori R, Sajiki H, Monguchi Y, Muraoka O, Tanabe G
Gifu Pharmaceutical University, Mitahora-higashi, Gifu 502-8585, Japan.
Nucleic Acids Symp Ser. 2000(44):113-4. doi: 10.1093/nass/44.1.113.
A novel reductive method for the chemical modification of nucleosides is described. Reaction of inosine derivatives with boran-THF resulted in the regioselective reduction of purine ring to afford the corresponding 2,3-dihydroinosine derivatives in moderate yields.
