Li H, Li X, Chu G, Liu J, Bi Z
Department of Nephrology, PUMC Hospital, CAMS, PUMC, Beijing 100730, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2000 Aug;22(4):395-7.
To study the difference between male and female patients with lupus nephritis(LN), we made a retrospective analysis. The clinical characteristics of 62 male patients with LN were compared with 62 female patients with LN. The result indicated the distribution of LN onset ages was different between male and female patients with LN. The incidence of LN was higher in the male than in female patients with SLE. Male patients were often misdiagnosed or diagnosed long after the onset of the disease. Arthritis and positive rate of ANA were less commonly occurred in female patients with LN. Other clinical and pathologic features of LN were similar in male and female patients. The response to treatment and prognosis of male patients with LN was relatively poor. So male patients with LN should be paid more attention to.
为研究狼疮性肾炎(LN)男性和女性患者之间的差异,我们进行了一项回顾性分析。将62例LN男性患者的临床特征与62例LN女性患者进行了比较。结果表明,LN男性和女性患者的发病年龄分布不同。LN在男性SLE患者中的发病率高于女性。男性患者常被误诊或在疾病发作后很长时间才被诊断出来。LN女性患者中关节炎和ANA阳性率较少见。LN的其他临床和病理特征在男性和女性患者中相似。LN男性患者对治疗的反应和预后相对较差。因此,LN男性患者应得到更多关注。