Ghatge S, Lee J, Smith I
Department of Anaesthesia, Keele University/University Hospital of North Staffordshire, Stoke-on-Trent, Staffordshire, UK.
Acta Anaesthesiol Scand. 2003 Sep;47(8):917-31. doi: 10.1034/j.1399-6576.2003.00196.x.
Sevoflurane has several properties which make it potentially useful as a day case anaesthetic. Following induction of anaesthesia with propofol, awakening from sevoflurane is faster compared to isoflurane, faster or similar compared to propofol and comparable (in the majority of studies) to desflurane. Subsequent recovery and discharge is generally similar following all agents. Sevoflurane may also be used to induce anaesthesia, which is generally well-received and causes less hypotension and apnoea compared to propofol. When used as a maintenance anaesthetic, the incidence of postoperative nausea and vomiting after sevoflurane is comparable to other inhaled anaesthetics, but this complication appears more common after inhaled inductions. The tolerability and low solubility of sevoflurane facilitate titration of anaesthesia and may reduce the need for opioid analgesia, which in turn may limit the occurrence of nausea and vomiting.
七氟烷具有多种特性，使其有可能作为日间手术麻醉剂使用。在用丙泊酚诱导麻醉后，与异氟烷相比，七氟烷麻醉苏醒更快；与丙泊酚相比，苏醒速度更快或相似；并且（在大多数研究中）与地氟烷相当。使用所有麻醉剂后，后续恢复和出院情况通常相似。七氟烷也可用于诱导麻醉，总体上效果良好，与丙泊酚相比，引起的低血压和呼吸暂停较少。当用作维持麻醉剂时，七氟烷术后恶心和呕吐的发生率与其他吸入性麻醉剂相当，但这种并发症在吸入诱导后似乎更常见。七氟烷的耐受性和低溶解度有助于麻醉的滴定，并可能减少对阿片类镇痛药的需求，这反过来可能会限制恶心和呕吐的发生。
