Sueters M, Arabin B, Oepkes D
Department of Obstetrics, Leiden University Medical Center, Leiden, The Netherlands.
Ultrasound Obstet Gynecol. 2003 Aug;22(2):186-9. doi: 10.1002/uog.190.
Fetomaternal hemorrhage (FMH) can cause severe anemia in the fetus. Untreated, this may cause hydrops or even fetal death. However, correct diagnosis of FMH followed by blood transfusion can prevent these life-threatening consequences. We describe two cases in which fetal anemia was suspected because of maternal reporting of decreased or absent fetal movements, the detection of a sinusoidal heart rate pattern and increased blood flow velocities of the middle cerebral artery and umbilical vein. Together with the Betke-Kleihauer test showing fetal cells in the maternal circulation, this led to the correct diagnosis of severe fetal anemia caused by FMH. A Cesarean section was performed within a few hours. Both neonates were severely anemic and received immediate blood transfusions. They are currently alive and well.
胎儿-母体出血（FMH）可导致胎儿严重贫血。若不治疗，这可能会导致胎儿水肿甚至死亡。然而，对FMH进行正确诊断并随后进行输血可预防这些危及生命的后果。我们描述了两例病例，由于母亲报告胎动减少或消失、检测到正弦型心率模式以及大脑中动脉和脐静脉血流速度增加，怀疑胎儿贫血。结合贝蒂-克莱豪尔试验显示母体循环中有胎儿细胞，这导致了由FMH引起的严重胎儿贫血的正确诊断。数小时内进行了剖宫产。两名新生儿均严重贫血并立即接受了输血。他们目前均存活且状况良好。
