[吸烟与胃癌关系的Meta分析]
[Meta-analysis of the relationship between smoking and stomach cancer].
作者信息
Liu Yun-xia, Wang Jie-zhen
机构信息
Institute of Evidence-Based Medicine, Shandong University, Jinan 250012, China.
出版信息
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2002 Dec;24(6):559-63.
OBJECTIVE
To explore the risk of stomach cancer associated with cigarette smoking.
METHODS
Meta-analysis was used to make formal summary statements about the relationship between smoking and stomach cancer. The results of the studies were analyzed by studied type(case-control study and cohort study) and gender(male and female). Homogeneity showed that random effect model should be selected to calculate the pooling relative risk (RR) and its corresponding 95% confidence interval (95%CI).
RESULTS
The total pooling RR(95%CI) was 2.14(1.12-4.06), while the total pooling RRs (95%CI) of male and female smoking with stomach cancer were 1.70 (1.34-2.14) and 1.83 (0.10-33.09), respectively.
CONCLUSIONS
Cigarette smoking is a risk factor for stomach cancer. Male smoking can increase risk of stomach cancer, however, the relationship between female smoking and stomach cancer should be studied further.
目的
探讨吸烟与胃癌的相关性。
方法
采用Meta分析对吸烟与胃癌的关系进行正式总结陈述。研究结果按研究类型（病例对照研究和队列研究）及性别（男性和女性）进行分析。齐性检验表明应选择随机效应模型计算合并相对危险度（RR）及其相应的95%置信区间（95%CI）。
结果
总合并RR（95%CI）为2.14（1.12 - 4.06），而男性和女性吸烟与胃癌的总合并RR（95%CI）分别为1.70（1.34 - 2.14）和1.83（0.10 - 33.09）。
结论
吸烟是胃癌的一个危险因素。男性吸烟会增加患胃癌的风险，然而，女性吸烟与胃癌的关系仍需进一步研究。
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