Ge Qin-sheng, Sun Mei-li
Department of Obstetric and Gynecology, PUMC Hospital, CAMS, PUMC, Beijing 100730, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2002 Oct;24(5):445-6.
We have gone through decades using hormone replacement therapy (HRT). The first problem encountered was increased endometrial cancer and solved by addition of progesterone. Now we are facing cardiovascular complications and how could we solve in the use of HRT. Research in vitro with HUAR and HUVEC and clinically seemed to show that small physiological doses might be the solution in protection of CVD.
我们使用激素替代疗法（HRT）已经有几十年了。最初遇到的问题是子宫内膜癌发病率增加，通过添加孕激素得以解决。现在我们正面临心血管并发症，在使用HRT时该如何解决呢。对人脐动脉平滑肌细胞（HUAR）和人脐静脉内皮细胞（HUVEC）的体外研究以及临床研究似乎表明，小生理剂量可能是预防心血管疾病的解决办法。
