Huang G Y, Gu D F, Duan X F, Xu X S, Gan W Q, Chen J C, Xie B Y, Wu X G
Division of Population Genetics and Prevention, Cardiovascular Institute, Fu Wai Hospital, CAMS, PUMC, Beijing 100037, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2001 Feb;23(1):15-8.
To study the changes of risk factors of cardiovascular disease in the rural community population after intervention.
The Beijing Fangshan cardiovascular prevention program was a community-based comprehensive intervention study which was launched from 1991 and ended in 2000 in five communities including three as intervention communities (IC) and two as control communities (CC) in Fangshan, Beijing suburb. The intervention measures were focused on health education and hypertension control. The changes of risk factors of cardiovascular disease in IC and CC were analyzed using random sample in the year 1991, 1995 and 1999, respectively. The risk factors include systolic and diastolic blood pressure (SBP and DBP), body mass index(BMI), serum total cholesterol(TC), triglyceride(TG), high-density lipoprotein cholesterol(HDL), smoking, and drinking.
From the year 1991 to 1999, the risk factors of cardiovascular disease such as SBP, DBP, smoking rate and drinking rate were reduced in the population of IC. For male in IC, the decline of SBP, DBP, smoking rate, and drinking rate were 1.6 mmHg, 1.1 mmHg, 14.5% (P < 0.01) and 3.7%, respectively. For female of IC, SBP and DBP declined 4.8 mmHg (P < 0.01) and 3.2 mmHg (P < 0.01), respectively. SBP, DBP and smoking rate in the population of CC had a little reduction while BMI, TC and TG increased in both IC and CC. During the period of 1991 to 1999, most cardiovascular risk factors in the population of IC had net reduction compared to that of CC.
Except for BMI and lipids, rural community intervention, as focused on health education and hypertension control, has resulted in the reduction of most risk factors of cardiovascular disease.
研究农村社区人群干预后心血管疾病危险因素的变化。
北京房山心血管病预防项目是一项基于社区的综合干预研究,于1991年启动,2000年结束,在北京郊区房山的五个社区开展,其中三个为干预社区(IC),两个为对照社区(CC)。干预措施主要集中在健康教育和高血压控制方面。分别于1991年、1995年和1999年在IC和CC中采用随机抽样的方法分析心血管疾病危险因素的变化。危险因素包括收缩压和舒张压(SBP和DBP)、体重指数(BMI)、血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL)、吸烟和饮酒。
1991年至1999年期间,IC人群中SBP、DBP、吸烟率和饮酒率等心血管疾病危险因素有所降低。IC组男性的SBP、DBP、吸烟率和饮酒率分别下降了1.6 mmHg、1.1 mmHg、14.5%(P<0.01)和3.7%。IC组女性的SBP和DBP分别下降了4.8 mmHg(P<0.01)和3.2 mmHg(P<0.01)。CC人群的SBP、DBP和吸烟率略有下降,而IC和CC两组的BMI、TC和TG均有所升高。1991年至1999年期间,与CC组相比,IC人群中的大多数心血管危险因素出现了净下降。
除BMI和血脂外,以健康教育和高血压控制为重点的农村社区干预已使大多数心血管疾病危险因素有所降低。