[Statistical approaches to gene mapping of human diseases].
作者信息
Sun H X, Fang F D
机构信息
National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, CAMS, PUMC, Beijing 100005, China.
出版信息
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2001 Feb;23(1):86-8, 96.
PMID:12905828
Abstract
Gene Mapping of human diseases, especially the complex genetic diseases, has been the difficulty and hotspot in medical genetics and gene study. In this article, the principle and application of several gene mapping methods are discussed, including linkage analysis (parametric and nonparametric linkage analysis), association study and linkage disequilibrium analysis.
摘要
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