Meyer-Heim Andreas D, Boltshauser Eugen
Division of Paediatric Neurology, University Children's Hospital, Steinwiesstrasse 75, CH-8032 Zurich, Switzerland.
Brain Dev. 2003 Sep;25(6):416-21. doi: 10.1016/s0387-7604(03)00029-9.
We are aware of only few reports addressing spontaneous intracranial haemorrhage (SICH) in non-selected series of children. This is a retrospective analysis of clinical presentation and outcome in 34 children with SICH seen in the period 1990-2000 in our hospital. Traumatic, neonatal and subdural haemorrhages were excluded. The majority (47%, 16/34) of SICH was caused by an arteriovenous malformation (AVM). SICH was presented as an acute event in 53% (17/32) of patients. Forty-seven percent (15/32) of the cases had protracted courses, which made the diagnosis difficult. In our series, younger children had less specific symptoms. Mortality (25%, 8/32) and morbidity were considerable, particularly in infratentorial haemorrhages, in aneurysms, in children younger than 3 years and in those with underlying haematological disorders.
我们仅知晓少数关于未经过筛选的儿童系列中自发性颅内出血（SICH）的报告。这是一项对1990年至2000年期间我院收治的34例SICH患儿的临床表现及预后的回顾性分析。创伤性、新生儿及硬膜下出血被排除在外。大多数（47%，16/34）SICH由动静脉畸形（AVM）引起。53%（17/32）的患者SICH表现为急性事件。47%（15/32）的病例病程迁延，使得诊断困难。在我们的系列研究中，年龄较小的儿童症状特异性较低。死亡率（25%，8/32）和发病率相当可观，尤其是幕下出血、动脉瘤、3岁以下儿童以及患有潜在血液系统疾病的儿童。
