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[儿童自发性颅内出血]

[Spontaneous intracranial hemorrhages in childhood].

作者信息

Veira C, Castro-Vilanova D, Ferreiro A, Sánchez-Suárez C, Cuadrado M L, Simón R, Mateos F

机构信息

Unidad de Neuropediatría, Hospital Doce de Octubre, Madrid, España.

出版信息

Rev Neurol. 1997 Sep;25(145):1381-2.

PMID:9377294
Abstract

INTRODUCTION

Spontaneous or non-traumatic intracranial haemorrhages seen in children of under 15 years old are most frequently due to cerebral vascular malformations, followed at a considerable distance by blood disorders, vasculopathies, tumours and the complications of radio-therapy.

OBJECTIVE

To present the cases of spontaneous and non-traumatic cerebral haemorrhage seen at our hospital.

MATERIAL AND METHODS

We reviewed all the paediatric cases of spontaneous cerebral haemorrhage diagnosed in our hospital over the previous sixteen years, excluding bleeding in the neonatal period. Computerized tomography was done in all cases, study of the cerebrospinal fluid, angiography and/or magnetic resonance in some cases.

RESULTS

We selected 44 patients, of who the aetiology could be determined in 30. Of these, 20 cases were due to vascular malformations, 7 were associated with haematological disorders, 2 with cerebral tumours and one case with meningococcal sepsis. The commonest form of presentation was that of an acute intracranial hypertension syndrome, also showing focal deficits, partial crises and meningism.

CONCLUSIONS

The commonest cause of spontaneous intracranial haemorrhage in children is due to rupture of a vascular malformation, namely an arterio-venous malformation. Angiography and/or magnetic resonance are the techniques of choice for diagnosis. The various causes of disorders of haemostasia also are important in giving rise to intracranial bleeding.

摘要

引言

15岁以下儿童出现的自发性或非创伤性颅内出血最常见的原因是脑血管畸形,其次是血液疾病、血管病变、肿瘤以及放射治疗并发症,但差距较大。

目的

介绍我院收治的自发性和非创伤性脑出血病例。

材料与方法

我们回顾了我院过去16年诊断的所有小儿自发性脑出血病例,不包括新生儿期出血。所有病例均进行了计算机断层扫描,部分病例进行了脑脊液检查、血管造影和/或磁共振成像。

结果

我们选取了44例患者,其中30例病因可明确。其中,20例因血管畸形,7例与血液系统疾病有关,2例与脑肿瘤有关,1例与脑膜炎球菌败血症有关。最常见的表现形式是急性颅内高压综合征,也表现为局灶性缺损、部分发作和脑膜刺激征。

结论

儿童自发性颅内出血最常见的原因是血管畸形破裂,即动静脉畸形。血管造影和/或磁共振成像是诊断的首选技术。止血障碍的各种原因在引发颅内出血方面也很重要。

相似文献

1
[Spontaneous intracranial hemorrhages in childhood].[儿童自发性颅内出血]
Rev Neurol. 1997 Sep;25(145):1381-2.
2
[Intraparenchymal hematomas: specific features in children].[脑实质内血肿:儿童的特殊特征]
Rev Neurol. 1998 Apr;26(152):561-3.
3
[Cerebral arterio-venous malformations in children under 10 years].10岁以下儿童的脑动静脉畸形
Rev Neurol. 1996 May;24(129):558-61.
4
[Cerebrovascular diseases in childhood--etiology, clinical aspects and prognosis].[儿童脑血管疾病——病因、临床特征及预后]
Fortschr Neurol Psychiatr. 1986 Feb;54(2):47-53. doi: 10.1055/s-2007-1001849.
5
[Arteriovenous malformations in children: a report of four cases].[儿童动静脉畸形:4例报告]
Rev Neurol. 2006;43(5):275-9.
6
[Primary intraventricular hemorrhage: an analysis of eight cases].[原发性脑室内出血:8例分析]
Rev Neurol. 1997 Feb;25(138):215-8.
7
Spontaneous cerebellar hemorrhage in children.儿童自发性小脑出血
J Forensic Sci. 2003 Jan;48(1):177-9.
8
[Current approaches in the treatment of intracranial hemorrhage].[颅内出血治疗的当前方法]
Lijec Vjesn. 1991 May-Jun;113(5-6):154-8.
9
[Magnetic resonance and magnetic resonance angiography in the diagnosis of vascular anomalies in childhood].[磁共振成像及磁共振血管造影术在儿童血管异常诊断中的应用]
Med Arh. 2000;54(5-6):307-9.
10
Cerebral venous sinus thrombosis in children: risk factors, presentation, diagnosis and outcome.儿童脑静脉窦血栓形成:危险因素、临床表现、诊断及预后
Brain. 2005 Mar;128(Pt 3):477-89. doi: 10.1093/brain/awh412. Epub 2005 Feb 7.

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