激光治疗I区阈值前及3期阈值ROP（早产儿视网膜病变）
Laser treatment of zone I prethreshold and stage 3 threshold retinopathy of prematurity.
作者信息
Récsán Zsuzsa, Vámos Rita, Salacz György
机构信息
Second Department of Ophthalmology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
出版信息
J Pediatr Ophthalmol Strabismus. 2003 Jul-Aug;40(4):204-7. doi: 10.3928/0191-3913-20030701-06.
PURPOSE
To analyze the structural outcomes of zone I prethreshold and stage 3 threshold retinopathy of prematurity following laser ablation.
PATIENTS AND METHODS
This nonrandomized observational case series evaluated 71 eyes of 36 infants who weighed less than 1,250 g at birth. Infants were treated at either prethreshold or threshold severity. The structural outcomes were compared using Fisher's exact test.
RESULTS
The structural outcome was favorable in 96% and 80% of the prethreshold and threshold groups, respectively (P = .069). When an unfavorable outcome was defined as dragging of the temporal vessels, the difference was significant (P = .0257).
CONCLUSION
Early treatment of zone I disease may result in a better structural outcome.
目的
分析I区阈值前和3期阈值ROP激光消融术后的结构转归。
患者与方法
本非随机观察性病例系列评估了36例出生体重小于1250g的婴儿的71只眼。婴儿接受阈值前或阈值期严重程度的治疗。使用Fisher精确检验比较结构转归。
结果
阈值前组和阈值组的结构转归良好率分别为96%和80%（P = 0.069）。当将不良转归定义为颞侧血管牵拉时，差异具有统计学意义（P = 0.0257）。
结论
I区疾病的早期治疗可能会带来更好的结构转归。
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