Chiang Chung-Jung, Fong Yi-Chin, Hsu Horng-Chaung
Department of Orthopedics, China Medical College Hospital, Taichung, Taiwan, ROC.
J Chin Med Assoc. 2003 May;66(5):307-10.
Extraskeletal mesenchymal chondrosarcoma is a rare malignancy. It is characteriged by a bimorphic histologic pattern, with a mesenchymal tissue mixed with malignant hyaline cartilage. It also has high incidence of local recurrence and distant metastasis. All cases have been reported fatal associated with this tumor in spite of complete surgical excision. A 35-year-old female presented with a palpable mass about 5 x 3 x 2.5 cm3 in size over her left forearm and was reported to be an extraskeletal mesenchymal chondrosarcoma. Marginal resection followed by regional radiotherapy was done. No local recurrence or distant metastasis was found two years after surgery. Thorough physical examination, series radiographic studies, and multiple sites of tumor biopsies before radical resection of the tumor may decrease the misdiagnostic rate for extraskeletal mesenchymal chondrosarcoma. Appropriate tumor treatment, close patient follow-up and timely treatment for local recurrence or distant metastasis may increase the survival rate.
骨外间叶性软骨肉瘤是一种罕见的恶性肿瘤。其特征为双相组织学模式，即间叶组织与恶性透明软骨混合。它还具有较高的局部复发和远处转移发生率。尽管进行了完整的手术切除，但所有报道的病例均与该肿瘤相关死亡。一名35岁女性，左前臂可触及一个大小约为5×3×2.5 cm³的肿块，据报道为骨外间叶性软骨肉瘤。进行了边缘切除并辅以局部放疗。术后两年未发现局部复发或远处转移。在肿瘤根治性切除前进行全面的体格检查、系列影像学检查以及多处肿瘤活检，可能会降低骨外间叶性软骨肉瘤的误诊率。适当的肿瘤治疗、密切的患者随访以及对局部复发或远处转移的及时治疗可能会提高生存率。
