Rethwilm A
Institut für Virologie, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, Dresden, 01307 Germany.
Curr Top Microbiol Immunol. 2003;277:1-26. doi: 10.1007/978-3-642-55701-9_1.
The replication strategy of foamy viruses diverges in many aspects from what is commonly accepted as the rules of retroviral replication. Although many questions on the details of the replication pathway are still unanswered, it appears that foamy viruses have adopted a strategy which functionally bridges the retroviral and the hepadnaviral replication pathways. A number of experimental findings in favour of the view that foamy viruses are reverse transcribing DNA viruses which integrate into the host cell genome are discussed.
泡沫病毒的复制策略在许多方面与普遍认可的逆转录病毒复制规则不同。尽管关于复制途径细节的许多问题仍未得到解答，但泡沫病毒似乎采用了一种在功能上连接逆转录病毒和嗜肝DNA病毒复制途径的策略。本文讨论了一些支持泡沫病毒是整合到宿主细胞基因组中的逆转录DNA病毒这一观点的实验结果。
