Hoffelt S Christopher, Marshall Lynn M, Garzotto Mark, Hung Arthur, Holland John, Beer Tomasz M
Department of Radiation Oncology, Oregon Health Sciences University, Portland, OR 97239, USA.
Int J Radiat Oncol Biol Phys. 2003 Sep 1;57(1):29-32. doi: 10.1016/s0360-3016(03)00509-1.
To compare CT and transrectal ultrasound (TRUS)-measured prostate volumes in patients with untreated prostate cancer.
Between 1995 and 1999, 48 consecutive patients at the Portland Veterans Affairs Medical Center were treated with external beam radiotherapy. In 36 of these patients, TRUS and CT measurements of the prostate volume were obtained before treatment and <6 months apart. The TRUS volume was calculated using the prolate ellipsoid formula. The CT volume was calculated from the contours of the prostate drawn by one physician, who was unaware of the TRUS volume calculation, on axial CT images.
The TRUS and CT prostate volume measurements correlated strongly (Pearson's correlation coefficient = 0.925, 95% confidence interval 0.856-0.961, p < 0.0001). The CT volume was consistently larger than the TRUS volume by a factor of approximately 1.5. In men with a TRUS prostate volume less than the median (<28 cm(3)), the CT/TRUS volume ratio was 1.7, and it was 1.4 for men whose volume was greater than the median. The CT volumes were correlated similarly with the TRUS volumes regardless of the CT slice interval.
A strong correlation was found between CT scan and TRUS measurement of the prostate volume; however, CT consistently overestimated the prostate volume by approximately 50% compared with TRUS.
比较未经治疗的前列腺癌患者经CT和经直肠超声（TRUS）测量的前列腺体积。
1995年至1999年间，波特兰退伍军人事务医疗中心连续48例患者接受了外照射放疗。其中36例患者在治疗前且间隔时间小于6个月时进行了TRUS和CT前列腺体积测量。TRUS体积采用长椭球体公式计算。CT体积由一位不知TRUS体积计算结果的医生在轴向CT图像上勾勒出前列腺轮廓后计算得出。
TRUS和CT测量的前列腺体积相关性很强（Pearson相关系数=0.925，95%置信区间0.856 - 0.961，p<0.0001）。CT体积始终比TRUS体积大，约为1.5倍。在TRUS前列腺体积小于中位数（<28 cm³）的男性中，CT/TRUS体积比为1.7，而体积大于中位数的男性该比值为1.4。无论CT切片间隔如何，CT体积与TRUS体积的相关性相似。
CT扫描和TRUS测量的前列腺体积之间存在很强的相关性；然而，与TRUS相比，CT始终将前列腺体积高估约50%。
