Liu Jiayin, Lu Guangxiu, Qian Yun, Mao Yundong, Ding Wei
Human Reproductive Engineering Lab, Xiang-Ya Medical College, Central South University, Changsha, Hunan, People's Republic of China.
Fertil Steril. 2003 Aug;80(2):447-9. doi: 10.1016/s0015-0282(03)00665-4.
To describe pregnancies that resulted from in vitro matured oocytes derived from stimulated IVF cycles before cancellation owing to poor response of gonadotropins.
Case report. University hospital.
PATIENT(S): Eight patients who underwent in vitro maturation.Immature oocyte retrieval, in vitro maturation of immature oocytes, fertilization, and ET. Luteal support with progesterone and plvyeron was given.
MAIN OUTCOME MEASURE(S): Pregnancy and live birth.
RESULT(S): Three pregnancies (two live births and another ongoing) were achieved after immature oocyte retrieval, in vitro maturation, fertilization with ICSI, and ET.
CONCLUSION(S): Immature oocyte retrieval from poor responders during stimulation, followed by in vitro maturation, may be an alternative before the cycle is canceled.
描述因促性腺激素反应不良而取消的体外受精（IVF）刺激周期中体外成熟卵母细胞所导致的妊娠情况。
病例报告。大学医院。
8例接受体外成熟的患者。进行未成熟卵母细胞采集、未成熟卵母细胞体外成熟、受精及胚胎移植（ET）。给予黄体酮和多聚乙二醇进行黄体支持。
妊娠及活产。
未成熟卵母细胞采集、体外成熟、卵胞浆内单精子注射（ICSI）受精及ET后，获得3次妊娠（2例活产，1例妊娠中）。
在刺激过程中从反应不良者中采集未成熟卵母细胞，随后进行体外成熟，可能是在周期取消前的一种替代方法。
