Mnif N, Hamrouni A, Iffenecker C, Oueslati S, Fruexer F, Doyon D, Hamza R
Service de radiologie, Hôpital Charles Nicolle, Tunis, Tunisie.
J Radiol. 2003 Jun;84(6):699-704.
Rathke's cleft cysts are non neoplastic lesions of the sellar area that seldom are symptomatic. Their incidence has been underestimated before magnetic resonance imaging (MRI). The aim of this work was to assess the value of MRI in the diagnosis and differential diagnosis of Rathke's cleft cyst based on a retrospective review of 12 cases and a review of the literature.
We retrospectively reviewed the MRI features of 12 patients with Rathke's cleft cyst collected over 4.5 years. Patients included ten females and two males (mean age: 39 years). The most common presentation was the association of dysmenorrhea and pituitary dysfunction. MRI examinations were performed using a 1.5 Tesla system, T1 and T2 weighted sequences performed before and after Gd- DTPA injection. Signal intensity, shape, size and location of the lesion were analyzed.
In all cases, MRI examination showed a cystic lesion of variable size and signal intensity. The cyst was purely intrasellar in nine cases and a suprasellar extension was noted in three cases. Five patients underwent surgery providing pathological confirmation, four underwent routine follow-up and three were lost of follow-up.
We conclude that MRI is an efficient tool for diagnosis, allowing appropriate medical decision making.
拉克氏裂囊肿是鞍区的非肿瘤性病变，很少有症状。在磁共振成像（MRI）出现之前，它们的发病率一直被低估。这项工作的目的是基于对12例病例的回顾性研究和文献复习，评估MRI在拉克氏裂囊肿诊断及鉴别诊断中的价值。
我们回顾性分析了4.5年间收集的12例拉克氏裂囊肿患者的MRI特征。患者包括10名女性和2名男性（平均年龄：39岁）。最常见的表现是痛经与垂体功能障碍。使用1.5特斯拉系统进行MRI检查，在注射钆喷酸葡胺（Gd-DTPA）前后进行T1加权和T2加权序列扫描。分析病变的信号强度、形状、大小和位置。
所有病例中，MRI检查均显示出大小和信号强度各异的囊性病变。9例囊肿完全位于鞍内，3例有鞍上延伸。5例患者接受了手术，病理得以证实，4例接受常规随访，3例失访。
我们得出结论，MRI是一种有效的诊断工具，有助于做出恰当的医疗决策。
