Weglewski Arkadiusz, Juryńczyk Jacek, Papierz Wielisław
Oddziału Neurologii Szpitala Wojewódzkiego im. Jana Pawła II w Bełchatowie.
Neurol Neurochir Pol. 2003 Jan-Feb;37(1):251-8.
Primary intracranial sarcomas are very rare and aggressive tumors. A case of a 40-year-old woman with primary leptomeningeal sarcomatosis is presented. Initially her clinical symptoms resembled those of a pseudo tumor cerebri. Neuroimaging did not allow establishing a diagnosis of leptomeninges neoplastic infiltration. The patient died 8 months since the onset of symptoms. A neuropathological examination revealed diffuse thickening of leptomeninges. Microscopically a widespread sarcomatous infiltration of the subarachnoid space was shown, as well as a neoplastic infiltration of the choroid plexus and of some perivascular spaces in the cerebral cortex. On the grounds of a review of the literature diagnostic problems, differential diagnosis and clinical course of primary leptomeningeal sarcomatosis are discussed.
原发性颅内肉瘤是非常罕见且具有侵袭性的肿瘤。本文报道了一例40岁患有原发性软脑膜肉瘤病的女性病例。最初，她的临床症状类似于假性脑瘤。神经影像学检查无法确诊软脑膜肿瘤浸润。患者自症状出现后8个月死亡。神经病理学检查显示软脑膜弥漫性增厚。显微镜下可见蛛网膜下腔广泛的肉瘤浸润，以及脉络丛和大脑皮质一些血管周围间隙的肿瘤浸润。基于文献回顾，讨论了原发性软脑膜肉瘤病的诊断问题、鉴别诊断及临床病程。
