Diehr Michael C, Cherner Mariana, Wolfson Tanya J, Miller S Walden, Grant Igor, Heaton Robert K
College of Business Administration, California State University San Marcos, San Marcos, CA, USA.
J Clin Exp Neuropsychol. 2003 Jun;25(4):571-85. doi: 10.1076/jcen.25.4.571.13876.
While the standard 200-item version of the Paced Auditory Serial Addition Task (PASAT) is a sensitive neuropsychological instrument, it can be quite aversive to some patients due to its length and progressively increasing difficulty. We present demographically-corrected norms for 50 and 100-item short-form versions in a sample of 560 neurologically normal adults. Age, education, and ethnicity (but not gender) were found to be significant predictors of performance. In a clinical sample of 786 HIV-infected adults, diagnostic accuracy of the 50, 100, and 200-item versions was essentially equivalent (using clinical ratings of a comprehensive neuropsychological battery as the gold standard, overall classification rates of the three PASAT versions were 71%, 74%, and 73%, respectively), with better specificity (89-92%) than sensitivity (46-53%). The 50-item version showed moderate ceiling effects, but the 100-item test did not. In a mixed clinical sample of 40 subjects, the 50-item version was administered more than twice as fast as the 200-item version, and was tolerated better (discomfort rating of 4.0 vs. 5.9 on a 10-point scale, p < .05). We conclude that in many cases the PASAT-50 and PASAT-100 provide equivalent diagnostic accuracy with a significant reduction in administration time and patient discomfort.
虽然标准的200项版本的听觉序列加法任务(PASAT)是一种敏感的神经心理学测试工具,但由于其长度和难度逐渐增加,对一些患者来说可能相当令人厌恶。我们在560名神经正常的成年人样本中给出了50项和100项简版的人口统计学校正常模。年龄、教育程度和种族(但不包括性别)被发现是表现的重要预测因素。在786名感染HIV的成年人临床样本中,50项、100项和200项版本的诊断准确性基本相当(以综合神经心理测试组的临床评级作为金标准,三个PASAT版本的总体分类率分别为71%、74%和73%),特异性(89 - 92%)优于敏感性(46 - 53%)。50项版本显示出中等程度的天花板效应,但100项测试没有。在40名受试者的混合临床样本中,50项版本的施测速度比200项版本快两倍多,且耐受性更好(在10分制量表上的不适评分为4.0对5.9,p <.05)。我们得出结论,在许多情况下,PASAT - 50和PASAT - 100提供了同等的诊断准确性,同时显著减少了施测时间和患者不适。