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秋水仙碱使一名患有肿瘤性淀粉样变性和基底细胞癌的患者的肾功能障碍和蛋白尿得到永久性改善。

Permanent improvement of renal dysfunction and proteinuria with colchicine in a patient with tumoral amyloidosis and basal cell carcinoma.

作者信息

Balal Mustafa, Seyrek Neslihan, Karayaylali Ibrahim, Paydaş Saime

机构信息

Cukurova University Faculty of Medicine, Department of Nephrology, Adana, Turkey.

出版信息

Ren Fail. 2003 Jul;25(4):677-80. doi: 10.1081/jdi-120022562.

Abstract

Basal cell carcinoma and amyloid deposition was reported not uncommonly, but renal failure and nephrotic syndrome were rare. Here in, we reported a 72 years old male patient with nephrotic syndrome, renal failure and relatively small basal cell carcinoma. In this patient toumoral excision caused temporary improvement. When the proteinuria reappeared, due to amyloid deposition in toumoral tissue, colchicine was began. With colchicine therapy permanent improvement of nephrotic syndrome was achieved in follow-up 18 months.

摘要

基底细胞癌和淀粉样沉积的报道并不少见,但肾衰竭和肾病综合征却很罕见。在此,我们报告了一名72岁男性患者,患有肾病综合征、肾衰竭以及相对较小的基底细胞癌。对该患者进行肿瘤切除后病情暂时改善。当蛋白尿再次出现时,由于肿瘤组织中存在淀粉样沉积,开始使用秋水仙碱治疗。经过18个月的随访,秋水仙碱治疗使肾病综合征得到了永久性改善。

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