Nga Nguyen Ngoc, Chai Sanders K, Bihn Ta Tuyet, Redding Gregory, Takaro Tim, Checkoway Harvey, Son Phan Han, Van Duong Khanh, Keifer Matthew, Trung Le Van, Barnhart Scott
National Institute of Occupational and Environmental Health, Ministry of Health, Ha Noi, Vietnam.
Pediatr Allergy Immunol. 2003 Aug;14(4):272-9. doi: 10.1034/j.1399-3038.2003.00043.x.
Childhood asthma and atopy prevalence patterns in the developing world are only beginning to be defined. No such information exists for Vietnam. Estimates would assist in anticipating health service needs as well as add to the growing database on global patterns of atopy. To estimate the prevalence of atopic symptoms in school children in Ha Noi, Vietnam, a cross-sectional survey was conducted of children aged 5- to 11-years-old in two schools using the parent self-administered International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. The response rate was 66.4% (969 responses). The overall prevalence of selected symptoms were: 'ever wheezed' 24.9%, 'wheezed in past 12 months' 14.9%, 'ever had asthma' 12.1%, 'doctor-diagnosed asthma' 13.9%, 'ever experienced allergic rhinitis (AR) symptoms' 34.9%, 'AR-conjunctivitis symptoms in past 12 months' 10.7%, 'ever had hay fever' 7.8%, 'doctor-diagnosed hay fever' 11.2%, 'ever had eczema' 3.3% and 'doctor-diagnosed eczema' 3.2%. Kappa statistics demonstrated high within symptom category consistency for 'ever had asthma/doctor-diagnosed asthma' (0.728) and 'ever had eczema/doctor-diagnosed eczema' (0.906). Age and gender adjusted odds ratios (OR) were also consistently significant across wheeze and allergic rhinitis symptom categories [highest OR = 10.10 (95% CI 6.23-16.35) between allergic rhinoconjunctivitis and wheeze in past 12 months]. There is a high prevalence of ISAAC-based symptoms in school children in Ha Noi, Vietnam, often above global averages. The high level of association between atopic symptoms suggests some degree of reliability and validity. Childhood atopy symptom prevalence in Vietnam is more similar to that in developed countries rather than developing countries.
发展中国家儿童哮喘和特应性疾病的流行模式才刚刚开始得到界定。越南尚无此类信息。相关估计将有助于预测卫生服务需求，并补充日益增长的全球特应性疾病模式数据库。为了估计越南河内学童特应性症状的患病率，使用家长自行填写的儿童哮喘和过敏国际研究（ISAAC）问卷，对两所学校5至11岁的儿童进行了横断面调查。应答率为66.4%（969份应答）。所选症状的总体患病率分别为：“曾喘息”24.9%，“在过去12个月内喘息”14.9%，“曾患哮喘”12.1%，“医生诊断为哮喘”13.9%，“曾出现过敏性鼻炎（AR）症状”34.9%，“在过去12个月内出现AR - 结膜炎症状”10.7%，“曾患花粉症”7.8%，“医生诊断为花粉症”11.2%，“曾患湿疹”3.3%，“医生诊断为湿疹”3.2%。卡方统计显示，“曾患哮喘/医生诊断为哮喘”（0.728）和“曾患湿疹/医生诊断为湿疹”（0.906）在症状类别内具有高度一致性。在喘息和过敏性鼻炎症状类别中，年龄和性别调整后的优势比（OR）也始终具有显著性[在过敏性鼻结膜炎和过去12个月内喘息之间，最高OR = 10.10（95%CI 6.23 - 16.35）]。越南河内学童基于ISAAC问卷的症状患病率很高，通常高于全球平均水平。特应性症状之间的高度关联性表明了一定程度的可靠性和有效性。越南儿童特应性症状患病率与发达国家更为相似，而非发展中国家。
