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[萨尔茨堡学龄儿童支气管哮喘、过敏性鼻炎和特应性皮炎的患病率及严重程度]

[Prevalence and severity of bronchial asthma, allergic rhinitis and atopic dermatitis in Salzburg school children].

作者信息

Eder W, Gamper A, Oberfeld G, Riedler J

机构信息

Pädiatrische Pneumologie, Kinderspital der LKA Salzburg.

出版信息

Wien Klin Wochenschr. 1998 Oct 16;110(19):669-77.

PMID:9823620
Abstract

As part of the International Study of Asthma and Allergies in Childhood (ISAAC), the aim of our study was to determine the prevalence and severity of asthma, allergic rhinitis and eczema in Austrian schoolchildren, using an international standardised protocol. A questionnaire concerning symptoms and prior diagnosis of asthma, allergic rhinitis and eczema was completed by the parents of 3581 children aged 6-8 years. 3357 adolescents aged 12-15 years completed a written and video questionnaire at school. We also measured airway responsiveness to 4.5% saline in 519 adolescents selected from 8 randomly chosen schools. The prevalence of "wheezing in the last 12 months" was 9.9% (6-8 yrs) and 11.9% (12-15 yrs), the prevalence of "ever having had a diagnosis of asthma" was 4.4% and 6.3% in the above mentioned age groups. While 80% of the pupils had mild asthma (defined as less than 4 attacks of wheezing in the last year), 13% had moderate (4-12 attacks) and 7% had severe asthma (> 12 attacks). The 12-month prevalence of symptoms of allergic rhinitis was 13.4% (6-8 yrs) and 22.5% (12-15 yrs), a diagnosis of "hayfever at any time" was reported in 8.9% and 20.4%. The prevalence of a chronic rash in the past year was 6.9% (6-8 yrs) and 6.7% (12-15 yrs), while 10.4% and 5%, respectively, had had a diagnosis of "eczema at any time". Among 12- to 15-year-old adolescents in the entire study population (n = 3371), the calculated prevalence of bronchial hyperresponsiveness was 13.7%. The prevalence of asthma symptoms, rhinitis and eczema in Austrian schoolchildren is higher than that estimated so far and similar to other European countries except the UK. Further, the results show that the 12-month prevalence of asthma symptoms is twice as high as the lifetime prevalence of a diagnosis of asthma, suggesting that the condition is frequently underdiagnosed.

摘要

作为儿童哮喘和过敏国际研究(ISAAC)的一部分,我们研究的目的是采用国际标准化方案,确定奥地利学童哮喘、过敏性鼻炎和湿疹的患病率及严重程度。3581名6至8岁儿童的家长完成了一份关于哮喘、过敏性鼻炎和湿疹症状及既往诊断的问卷。3357名12至15岁的青少年在学校完成了一份书面及视频问卷。我们还对从8所随机选取的学校中挑选出的519名青少年进行了4.5%盐水气道反应性测量。“过去12个月内喘息”的患病率在6至8岁组为9.9%,在12至15岁组为11.9%;上述年龄组中“曾被诊断为哮喘”的患病率分别为4.4%和6.3%。虽然80%的学生患有轻度哮喘(定义为过去一年喘息发作少于4次),但13%患有中度哮喘(4至12次发作),7%患有重度哮喘(超过12次发作)。过敏性鼻炎症状的12个月患病率在6至8岁组为13.4%,在12至15岁组为22.5%;“曾患花粉热”的报告患病率分别为8.9%和20.4%。过去一年慢性皮疹的患病率在6至8岁组为6.9%,在12至15岁组为6.7%;而“曾被诊断为湿疹”的患病率分别为1 .4%和5%。在整个研究人群(n = 3371)的12至15岁青少年中,计算得出的支气管高反应性患病率为13.7%。奥地利学童哮喘症状、鼻炎和湿疹的患病率高于迄今估计的水平,且除英国外与其他欧洲国家相似。此外,结果显示哮喘症状的12个月患病率是哮喘诊断终生患病率的两倍,这表明该疾病经常被漏诊。

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