阴道良性混合瘤：病例报告及扩展的免疫组化分析

Benign mixed tumor of the vagina: case report with expanded immunohistochemical profile.

作者信息

Murdoch F, Sharma R, Al-Nafussi A

机构信息

Department of Pathology, Stirling Royal Infirmary, Scotland, UK.

出版信息

Int J Gynecol Cancer. 2003 Jul-Aug;13(4):543-7. doi: 10.1046/j.1525-1438.2003.13309.x.

DOI:10.1046/j.1525-1438.2003.13309.x

PMID:12911736

Abstract

We present a case of benign mixed tumor of the vagina with its typical clinicopathologic and expanded immunohistochemical features. The strong coexpression of the mesenchymal spindle cell component with epithelial markers such as CK7, together with strong CD10, Bcl2, and estrogen and progesterone receptors favors a mullerian derived tumor. The tumor is best labeled as benign mixed mullerian tumor as originally designated.

摘要

我们报告一例阴道良性混合瘤，展示其典型的临床病理特征及扩展的免疫组化特征。间充质梭形细胞成分与细胞角蛋白7等上皮标志物的强共表达，以及强阳性的CD10、Bcl2、雌激素和孕激素受体，提示该肿瘤起源于苗勒管。该肿瘤最好按照最初的命名标记为良性混合性苗勒管肿瘤。