Steinberg L M, Odusola F, Mandel I D
Columbia University School of Dental and Oral Surgery, NY 10032.
Clin Prev Dent. 1992 Sep-Oct;14(5):31-4.
The objective of this study was to investigate the effects of xylitol and sorbitol sweetened chewing gums on plaque accumulation, gingival inflammation and remineralizing potential of plaque following six weeks of use. Twenty-eight consenting individuals were randomly assigned to each of three phases (six weeks in duration) consisting of chewing xylitol gum, chewing sorbitol gum and a non-chewing phase. Subjects chewed one stick after every meal and at two other times for a total of five sticks per day. At the completion of each treatment phase, plaque and gingival indexes were performed and plaque was later collected. Calcium concentration in plaque was determined by atomic absorption spectophotometry. Reductions in plaque indexes were significant for both xylitol gum (p < 0.001) and sorbitol gum (p < 0.05) when compared to the no chewing period. The gingival indexes reflected a decrement in gingival inflammation with both xylitol and sorbitol, though only sorbitol values were statistically significant (p < 0.05). Chewing xylitol and sorbitol gums reduced plaque accumulation and gingival inflammation. In addition, both gums enhanced the remineralization potential of plaque. Xylitol gum showed a superior effect with respect to remineralization potential and plaque reduction. Sorbitol gum had a superior effect on gingival health but not significantly so.
本研究的目的是调查使用六周后,木糖醇和山梨醇甜味口香糖对牙菌斑积聚、牙龈炎症以及牙菌斑再矿化潜力的影响。28名同意参与的个体被随机分配到三个阶段(为期六周)中的每个阶段,这三个阶段分别为咀嚼木糖醇口香糖、咀嚼山梨醇口香糖和非咀嚼阶段。受试者每餐饭后及其他两个时间各咀嚼一根口香糖,每天共咀嚼五根。在每个治疗阶段结束时,进行牙菌斑和牙龈指数检测,随后收集牙菌斑。通过原子吸收分光光度法测定牙菌斑中的钙浓度。与不咀嚼阶段相比,木糖醇口香糖(p < 0.001)和山梨醇口香糖(p < 0.05)的牙菌斑指数均显著降低。牙龈指数显示,木糖醇和山梨醇均能减轻牙龈炎症,不过只有山梨醇的值具有统计学意义(p < 0.05)。咀嚼木糖醇和山梨醇口香糖可减少牙菌斑积聚和牙龈炎症。此外,两种口香糖均增强了牙菌斑的再矿化潜力。木糖醇口香糖在再矿化潜力和减少牙菌斑方面显示出更优的效果。山梨醇口香糖对牙龈健康有更优的效果,但差异不显著。