Wang X Z, Ma Y J, Zheng J F, Qin H Y
Department of Urology, Changhai Hospital, Second Military Medical University.
Chin Med J (Engl). 1992 Oct;105(10):856-9.
The DNA-Malignancy-Grade(DNA-MG) of paraffin-embedded tumor specimens from 38 patients with bladder tumor was determined by image cytometry. A good correlation was found of DNA-MG with clinical staging and histopathological grading. The DNA-MG of T1 and G1 bladder tumor was less than 3.00, while that of T3-4 and G3 bladder tumor was greater than 3.00. The 5-year survival of patients with DNA-MG < 3.00 and > 3.00 was 100% and 36.9%, respectively. The data indicate that DNA-MG plays an important role in the assessment of the prognosis and the planning of treatment.
采用图像细胞术测定了38例膀胱肿瘤患者石蜡包埋肿瘤标本的DNA恶性度分级（DNA-MG）。发现DNA-MG与临床分期和组织病理学分级具有良好的相关性。T1期和G1级膀胱肿瘤的DNA-MG小于3.00，而T3-4期和G3级膀胱肿瘤的DNA-MG大于3.00。DNA-MG<3.00和>3.00的患者5年生存率分别为100%和36.9%。数据表明，DNA-MG在预后评估和治疗方案制定中起重要作用。
