Yamashita S, Taniguchi K, Suzu H, Yushita Y, Sakuragi T, Kanetake H, Shindo K, Saito Y, Hori T, Tasaki T
Department of Urology, Nagasaki University School of Medicine.
Hinyokika Kiyo. 1990 Oct;36(10):1149-54.
A clinical and histopathological investigation was made on 170 patients with bladder cancer who underwent total cystectomy at our institutions between 1982 and 1986. The overall 5-year survival rates of patients with pTis + pTa, pT1, pT2, pT3, pT3b and pT4 were 100, 71.8, 60.7, 39.2, 31.4 and 0% respectively, those of patients with G1, G2 and G3 were 100%, 67.6%, 35.7% respectively. As for histopathological growth and spread pattern (INF), intramural lymphatic invasion (ly) and venous invasion (v), INF beta, INF gamma, ly2, v (+) showed the worst prognosis. These histopathological factors were considered to be closely correlated to each other. Studies on these histopathological factors are very important in planning the subsequent therapy.
对1982年至1986年间在我们机构接受全膀胱切除术的170例膀胱癌患者进行了临床和组织病理学调查。pTis + pTa、pT1、pT2、pT3、pT3b和pT4患者的总体5年生存率分别为100%、71.8%、60.7%、39.2%、31.4%和0%，G1、G2和G3患者的总体5年生存率分别为100%、67.6%、35.7%。至于组织病理学生长和扩散模式（INF）、壁内淋巴浸润（ly）和静脉浸润（v），INFβ、INFγ、ly2、v（+）显示出最差的预后。这些组织病理学因素被认为彼此密切相关。对这些组织病理学因素的研究在规划后续治疗中非常重要。
