[杜氏肌营养不良症肌纤维分型的研究]

[A study of muscle fibers typing on Duchenne muscular dystrophy].

作者信息

Gao F Q

机构信息

PLA. Generar Hospital, Beijing.

出版信息

Zhonghua Shen Jing Jing Shen Ke Za Zhi. 1992 Oct;25(5):273-7, 316.

PMID:1291247

Abstract

Quantitative analysis of muscle fibers typing in 15 cases of Duchenne muscular dystrophy has been done. Mean diameter, area, variability coefficient were estimated by computer. The results show that type IIC fibers were remarkably increased and type IIB fibers was deficiency in DMD. Atrophy and hypertrophy occurred in different typing fibers. The results indicated that DMD has a prominent atrophy and hypertrophy and active regenerating process.

摘要

对15例杜氏肌营养不良症患者的肌纤维类型进行了定量分析。通过计算机估算平均直径、面积、变异系数。结果显示，在杜氏肌营养不良症中，IIC型纤维显著增加，IIB型纤维缺乏。不同类型的纤维出现萎缩和肥大。结果表明，杜氏肌营养不良症存在明显的萎缩、肥大以及活跃的再生过程。