来自海绵紫沙扁虫的两种新的溴酪氨酸衍生代谢物。
Two new bromotyrosine-derived metabolites from the sponge Psammaplysilla purpurea.
作者信息
Goud Thirumani Venkateshwar, Srinivasulu Masuna, Reddy Vanimireddy Lakshmi Niranjan, Reddy Adelli Vijender, Rao Tadikamalla Prabhakar, Kumar Dondapati Srujan, Murty Upadhyayula Suryanaramyana, Venkateswarlu Yenamandra
机构信息
Natural Products Laboratory, Organic Division-I, Indian Institute of Chemical Technology.
出版信息
Chem Pharm Bull (Tokyo). 2003 Aug;51(8):990-3. doi: 10.1248/cpb.51.990.
Two new bromotyrosine-derived metabolites (1, 2) have been isolated along with the known compounds 3,5-dibromo-4-methoxyphenylacetonitrile, 3-bromo-4-methoxyphenylacetonitrile, 3-bromo-4-hydroxyphenylacetonitrile, 1-hydroxyuracil, 1-methoxyhemibastadin 2, purpuramine H and a steroid 5alpha,8alpha-epidioxycholest-6-en-3beta-ol from the sponge Psammaplysilla purpurea. Compounds 1 and 2 were characterized by interpretation of their spectral data. The antibacterial activity of these compounds is summarized.
从紫色沙海绵（Psammaplysilla purpurea）中分离出了两种新的溴酪氨酸衍生代谢物（1和2），以及已知化合物3,5-二溴-4-甲氧基苯乙腈、3-溴-4-甲氧基苯乙腈、3-溴-4-羟基苯乙腈、1-羟基尿嘧啶、1-甲氧基半bastadin 2、紫癜胺H和一种甾体5α,8α-环氧胆甾-6-烯-3β-醇。通过对化合物1和2的光谱数据进行解析对其进行了表征。总结了这些化合物的抗菌活性。
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