Shim Sang Hee, Kim Ju Sun, Kang Sam Sik
Natural Products Research Institute and College of Pharmacy, Seoul National University, Seoul, Korea.
Chem Pharm Bull (Tokyo). 2003 Aug;51(8):999-1002. doi: 10.1248/cpb.51.999.
Four new and five known norditerpenoid alkaloids were isolated from the processed tubers of Aconitum carmichaeli. The new alkaloids are 14-O-cinnamoylneoline (3), 14-O-anisoylneoline (4) 14-O-veratroylneoline (5), and lipo-14-O-anisoylbikhaconine (8). The known alkaloids are neoline (1), 14-O-acetylneoline (2), foresaconitine (6), crassicauline A (7), and lipohypaconitine (9). Alkaloids 2, 6, and 7 were isolated from this plant for the first time. The structures of the new alkaloids were established by spectroscopic and chemical methods.
从制川乌的块根中分离得到了4个新的和5个已知的去甲二萜生物碱。新生物碱为14-O-肉桂酰新乌头碱（3）、14-O-茴香酰新乌头碱（4）、14-O-藜芦酰新乌头碱（5）和脂-14-O-茴香酰二氢高乌头碱（8）。已知生物碱为新乌头碱（1）、14-O-乙酰基新乌头碱（2）、前乌头碱（6）、粗茎乌甲素（7）和脂去甲乌药碱（9）。生物碱2、6和7首次从该植物中分离得到。通过光谱和化学方法确定了新生物碱的结构。
