Gorincour G, Dugougeat-Pilleul F, Bouvier R, Lorthois-Ninou S, Devonec S, Gaucherand P, Pracros J P, Guibaud L
Department of Pediatric and Fetal Imaging, Hôpital Debrousse, Lyon, Cedex, France.
Prenat Diagn. 2003 Aug;23(8):690-3. doi: 10.1002/pd.671.
To describe a cervical neuroblastoma revealed in the prenatal period.
We were recently confronted with a case of fetal solid neck mass suggestive of teratoma, which proved postnatally to be a neuroblastoma. Combining this case with a review of recent literature, we have evaluated the diagnostic tools required for increased precision in the prenatal diagnosis and perinatal management of fetal solid neck masses.
Detailed ultrasound and MRI of fetal neck and liver, in conjunction with amniocentesis for measurement of homovanillic acid levels, should enable fetal medical practitioners to consider the diagnosis of fetal cervical neuroblastoma.
Fetal cervical neuroblastoma is an extremely rare condition that has not been previously reported, but should be considered in the presentation of fetal solid neck masses.
描述一例产前发现的颈部神经母细胞瘤。
我们最近遇到一例胎儿颈部实性肿块,提示为畸胎瘤,产后证实为神经母细胞瘤。将该病例与近期文献回顾相结合,我们评估了提高胎儿颈部实性肿块产前诊断和围产期管理准确性所需的诊断工具。
对胎儿颈部和肝脏进行详细的超声和磁共振成像(MRI)检查,同时进行羊膜穿刺术测量高香草酸水平,应能使胎儿医学从业者考虑胎儿颈部神经母细胞瘤的诊断。
胎儿颈部神经母细胞瘤是一种极为罕见的疾病,此前未见报道,但在胎儿颈部实性肿块的表现中应予以考虑。