Abramson S J, Berdon W E, Ruzal-Shapiro C, Stolar C, Garvin J
Department of Pediatric Radiology, Babies Hospital, Columbia-Presbyterian Medical Center, New York, NY 10032.
Pediatr Radiol. 1993;23(4):253-7. doi: 10.1007/BF02010908.
Cervical neuroblastoma, a disease primarily of infants, has a favorable prognosis. Eleven patients are reported. Clinical presentations (other than mass) included stridor and swallowing problems. Masses when felt were commonly mistaken for infectious adenitis. Imaging studies (US, CT, MRI) showed solid masses with vascular displacement and narrowing; intraspinal extension was absent though extension into the adjacent sites of mediastinum and skull occurred. Horner syndrome was seen in five patients with accompanying heterochromia iridis in one. Five tumors had calcification. A high index of suspicion will lead to biopsy and less delay in diagnosis once a mass is felt or imaged.
颈部神经母细胞瘤主要发生于婴儿,预后良好。本文报告了11例患者。临床表现(除肿块外)包括喘鸣和吞咽困难。触及的肿块常被误诊为感染性腺炎。影像学检查(超声、CT、MRI)显示实性肿块伴有血管移位和狭窄;未发现脊髓内扩展,但肿块可延伸至纵隔和颅骨的相邻部位。5例患者出现霍纳综合征,其中1例伴有虹膜异色。5个肿瘤有钙化。一旦触及肿块或进行影像学检查,高度怀疑将有助于活检并减少诊断延迟。