Ostrowska Lucyna, Czapska Danuta, Karczewski Jan
Zakład Higieny i Epidemiologii Akademii Medycznej w Białymstoku.
Pol Merkur Lekarski. 2003 Mar;14(81):224-8.
The aim of the study was to determine the relationship between selected risk factors and the incidence of breast carcinoma in women living in the province of Podlasie, with special regard to obesity. The study involved 90 patients with breast carcinoma and 96 without the cancer. A questionnaire was used to evaluate risk factors of the disease. The mean age was 55 years in the carcinoma group and 53 years in the control group. Increased body mass was an essential risk factor of the cancer, which was statistically confirmed by multifactorial analysis. Statistically significant differences were also associated with family history of breast and other cancers, abortions, childlessness, early menarche and late menopause. Multidimensional regression analysis was performed with the application of the logistic model. Statistically significant factors included the history of cigarette smoking, abortions, overweight or obesity (high BMI index), family history of cancers (of the breast and other). The outcome of the multifactorial analysis allows for the assumption that the accumulation of these five factors in one patient increases the risk of breast carcinoma 9.45 times.