Grom Andreas, Baron Thomas W, Brunner Michael, Giesler Ulrich, Faber Thomas S, Bode Christoph, Zehender Manfred
Universiätsklinikum Freiburg, Innere Medizin III, Kardiologie und Angiologie, Freiburg, Germany. grom@med 1.ukl.uni-freiburg.de
Pacing Clin Electrophysiol. 2003 Jul;26(7 Pt 1):1472-8. doi: 10.1046/j.1460-9592.2003.t01-1-00213.x.
Present-day ICD systems offer the possibility to reconstruct an intrathoracic 6-lead ECG (IT-ECG), using the defibrillator coils in the right ventricle and superior vena cava and the left-laterally positioned ICD as electrodes according to Einthoven and Goldberger. The aim of this study was to assess the feasibility of (1). automated P wave recognition in the IT-ECG without an additional atrial electrode as the basis of AV synchronous ventricular pacing (VDD) and for improved differentiation between supraventricular tachyarrhythmias and, (2). the automated detection of pacing evoked atrial potentials (EAP) in dual chamber ICDs as the basis for atrial "autocapture"pacing systems. In 27 patients during ICD implanation intraoperatively, the IT-ECG was digitally recorded. A recently established algorithm for automatic P wave and EAP detection correctly identified 1663/1672 (99.5%) P waves (oversensing rate 0.6%) and 543/554 (98.0%) EAP (no oversensing). During subthreshold atrial stimulation, 405/412 (98.3%) P waves were correctly identified (oversensing due to pacemaker spikes, n = 421, without subsequent EAP, 1.9%,n = 8). During stimulated ventricular tachycardia in 26/27 patients retrograde P wave or AV dissociation were identified. The 6-lead IT-ECG, easily implementable in ICD systems, is a diagnostic tool providing reliable information about atrial activation, serving as a basis for VDD pacing in single chamber ICD systems, allowing reliable EAP recognition that enables atrial "autocapture"pacing in dual chamber ICDs, and improves the differentiation between supraventricular and ventricular tachycardia.
当今的植入式心脏除颤器(ICD)系统提供了重建胸内6导联心电图(IT-ECG)的可能性,根据艾因托芬和戈德伯格的方法,使用右心室和上腔静脉中的除颤线圈以及左侧位置的ICD作为电极。本研究的目的是评估:(1)在没有额外心房电极的IT-ECG中自动识别P波作为房室同步心室起搏(VDD)的基础以及用于改善室上性快速心律失常之间的鉴别诊断的可行性;(2)在双腔ICD中自动检测起搏诱发的心房电位(EAP)作为心房“自动夺获”起搏系统的基础。在27例患者ICD植入术中,对IT-ECG进行了数字记录。一种最近建立的自动检测P波和EAP的算法正确识别了1663/1672(99.5%)个P波(过感知率0.6%)和543/554(98.0%)个EAP(无过感知)。在阈下心房刺激期间,405/412(98.3%)个P波被正确识别(因起搏器脉冲导致过感知,n = 421,无后续EAP,1.9%,n = 8)。在26/27例患者的刺激室性心动过速期间,识别出逆行P波或房室分离。6导联IT-ECG可轻松应用于ICD系统,是一种提供有关心房激动可靠信息的诊断工具,可作为单腔ICD系统中VDD起搏的基础,允许可靠识别EAP,从而实现双腔ICD中的心房“自动夺获”起搏,并改善室上性和室性心动过速之间的鉴别诊断。