Al-Hussaini Abdulrahman A, Machida Helen M, Butzner J Decker
Department of Pediatrics, Alberta Children's Hospital, Calgary, Canada.
Can J Gastroenterol. 2003 Jul;17(7):445-7. doi: 10.1155/2003/368754.
A five-year-old boy presented to his family physician with painless swelling of both lips. One year later he developed abdominal pain, nonbloody diarrhea, weight loss and joint pains. Colonoscopic examination demonstrated patchy erythema, friability and multiple aph-thous ulcers consistent with the appearance of Crohn's colitis, and treatment with prednisone was initiated. Colonic biopsies displayed a chronic inflammatory cell infiltrate, focal cryptitis and fissure formation. The patient's lip swelling relapsed on multiple occasions when steroids were tapered, despite minimal intestinal symptoms of Crohn's disease. The objective of the present report is to alert physicians to this unusual presentation of Crohn's disease and that cheilitis may run a protracted course.
一名五岁男孩因双唇无痛性肿胀就诊于家庭医生。一年后，他出现腹痛、非血性腹泻、体重减轻和关节疼痛。结肠镜检查显示有散在红斑、脆性增加和多个阿弗他溃疡，符合克罗恩病性结肠炎的表现，遂开始使用泼尼松治疗。结肠活检显示有慢性炎症细胞浸润、局灶性隐窝炎和裂隙形成。尽管克罗恩病的肠道症状轻微，但当逐渐减少类固醇剂量时，患者的唇部肿胀多次复发。本报告的目的是提醒医生注意克罗恩病的这种不寻常表现，且唇炎可能病程迁延。
