Coenen C, Börsch G, Müller K M, Fabry H
Department of Medicine, St. Josef-Hospital, Ruhr-University, Bochum, Federal Republic of Germany.
Dis Colon Rectum. 1988 Jul;31(7):548-52. doi: 10.1007/BF02553730.
The case of a 14-year-old boy who had oral ulcers with histologic proof of granulomatous disease nine months before the diagnosis of intestinal Crohn's disease is presented. Additional extraintestinal manifestations of this case were cheilitis, anal fissures, and "metastatic" disease to the umbilicus. The diagnosis was established after the onset of abdominal symptoms. All manifestations responded rapidly to systemic prednisone, sulfasalazine, and metronidazole.
本文介绍了一名14岁男孩的病例，该男孩在被诊断为肠道克罗恩病九个月前出现口腔溃疡，并有肉芽肿性疾病的组织学证据。该病例的其他肠外表现包括唇炎、肛裂以及脐部的“转移性”疾病。在出现腹部症状后确诊。所有表现对全身性泼尼松、柳氮磺胺吡啶和甲硝唑反应迅速。
