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胰腺神经内分泌肿瘤

Neuroendocrine tumors of the pancreas.

作者信息

Van Nieuwenhove Y, Vandaele S, Op de Beeck B, Delvaux G

机构信息

Department of Abdominal Surgery, Vrije Universiteit Brussel, Laarbeeklaan 101, B-1090 Brussels, Belgium.

出版信息

Surg Endosc. 2003 Oct;17(10):1658-62. doi: 10.1007/s00464-002-9268-x. Epub 2003 Aug 15.

Abstract

BACKGROUND

The benefits of associating magnetic resonance imaging (MRI) and laparoscopy for localizing and treating neuroendocrine pancreatic tumors (NEPTs) have been poorly documented.

METHODS

In a retrospective study, eight patients with a mean age of 48 years were operated on for a NEPT. MRI was used to localize the lesions. In all patients a laparoscopic resection was carried out. Laparoscopic ultrasonography (LUS) was used during most operations.

RESULTS

The tumor was clearly localized by MRI in seven patients, and LUS showed the lesion in another patient whose preoperative MRI had been unsuitable. Three enucleations, three spleen-preserving caudal pancreatectomies, and two caudal pancreatectomies with splenectomy were carried out. There were no conversions and the mean operating time was 260 min, with a mean blood loss of 180 ml. The mean hospital stay was 7 days. There were no minor nor major complications during the hospitalization period. However, a pancreatic abscess was diagnosed in one patient 1 month later, requiring an urgent laparotomy.

CONCLUSION

MRI as well as LUS are indeed suitable techniques to localize NEPTs. Moreover, the minimally invasive approach ensured an adequate treatment with a more comfortable and short postoperative recovery.

摘要

背景

关于磁共振成像(MRI)与腹腔镜检查联合用于定位和治疗神经内分泌胰腺肿瘤(NEPTs)的益处,相关文献报道较少。

方法

在一项回顾性研究中,8例平均年龄48岁的患者因NEPT接受手术治疗。使用MRI定位病变。所有患者均接受腹腔镜切除术。大多数手术中使用了腹腔镜超声检查(LUS)。

结果

7例患者的肿瘤通过MRI清晰定位,另1例患者术前MRI检查结果不理想,LUS显示了病变。实施了3例肿瘤剜除术、3例保留脾脏的胰尾切除术以及2例联合脾脏切除的胰尾切除术。无中转开腹情况,平均手术时间为260分钟,平均失血量为180毫升。平均住院时间为7天。住院期间无轻微或严重并发症发生。然而,1例患者在术后1个月被诊断出胰腺脓肿,需要紧急剖腹手术。

结论

MRI和LUS确实是定位NEPTs的合适技术。此外,微创方法确保了充分的治疗,术后恢复更舒适且时间短。

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