Boominathan R, Devi B Parimala, Mandal Subhash C
Division of Pharmacognosy & Phytochemistry, Department of Pharmaceutical Technology, Faculty of Engineering & Technology, Jadavpur University, Calcutta, India.
Phytother Res. 2003 Aug;17(7):838-9. doi: 10.1002/ptr.1257.
The present study was carried out to evaluate the antitussive potential of methanol extract of Ionidium suffruticosam Ging. (Violaceae) which was investigated for its effect on a cough model induced by sulfur dioxide gas in albino mice. It exhibited significant dose-dependent antitussive activity when compared with the control, 250 and 500 mg/kg (p.o.) of the extract showing 28.37% and 54.16% inhibition of the cough with respect to control group. The antitussive activity of the extract was comparable to that of codeine phosphate, a prototype antitussive agent.
