Christiaans M H, Ernst J M P G, Suttorp M J, van den Berg J C, Overtoom T Th C, Kelder J C, Mauser H W, Ackerstaff R G A
Department of Clinical Neurophysiology, St Antonius Hospital, Nieuwegein, Utrecht 3430 EM, The Netherlands.
Eur J Vasc Endovasc Surg. 2003 Aug;26(2):141-4. doi: 10.1053/ejvs.2002.1974.
To prospectively document the incidence, location, risk factors for and clinical consequences of restenosis after carotid artery angioplasty and stenting (CAS).
Serial duplex and neurological examinations were performed in 217 patients one day (n = 216), 3 (n = 189), 12 (n = 129) and 24 (n = 48) months, after CAS. The relationship between patient, lesion and procedure variables and restenosis was determined at 12 months.
The prevalence of restenosis > or = 50% was 14, 16, 18, and 21%, respectively, and was only significantly related with loss of proximal stent apposition (odds ratio 3.4, 95% confidence interval: 1.0-11.7, p < 0.05). Four restenoses were symptomatic.
Restenosis after CAS is common, unpredictable but infrequently symptomatic.
前瞻性记录颈动脉血管成形术和支架置入术(CAS)后再狭窄的发生率、部位、危险因素及临床后果。
对217例患者在CAS术后1天(n = 216)、3个月(n = 189)、12个月(n = 129)和24个月(n = 48)时进行系列双功超声和神经学检查。在12个月时确定患者、病变和手术变量与再狭窄之间的关系。
再狭窄≥50%的发生率分别为14%、16%、18%和21%,且仅与近端支架贴壁不良显著相关(优势比3.4,95%置信区间:1.0 - 11.7,p < 0.05)。4例再狭窄有症状。
CAS术后再狭窄常见、不可预测但很少有症状。