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社会经济地位、地理位置、有症状的颈动脉供血区疾病与颈动脉内膜切除术之间的关系。

The relationship between socio-economic status, geography, symptomatic carotid territory disease and carotid endarterectomy.

作者信息

MacKenzie R, Nimmo F, Bachoo P, Alozairi O, Brittenden J

机构信息

Department of Vascular Surgery, University of Aberdeen, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, Scotland, UK.

出版信息

Eur J Vasc Endovasc Surg. 2003 Aug;26(2):145-9. doi: 10.1053/ejvs.2002.1949.

Abstract

OBJECTIVE

recent evidence suggests a strong association between socio-economic status and atherosclerosis. However, little information exists on the relationship between socio-economic status, symptomatic carotid disease and rates of carotid endarterectomy (CEA). The aim was to evaluate the Carstair Deprivation Score (CDS) of (1) patients admitted with symptomatic carotid disease, and (2) those undergoing CEA in one health board.

METHOD

the CDS score was determined from the post-codes of all patients admitted with a diagnosis of transient ischaemic attack (TIA) or stroke due to cerebral infarction (ISD 9 codes 433.1, 433.09, 435, 437.1; ICD-10: 165.2, 163, 163.2, G45.1, G45.3, G45.9) between 1st April 1995 and 31st March 2000. Expected and actual rates for each of the CDS (1 to 7) were determined by direct and indirect methods of standardisation allowing for age and sex. A similar analysis was performed for patients undergoing carotid endarterectomy. Results were analysed using the Mantel-Haenszel test. Only first time admissions and CEA were included.

RESULTS

1203 patients were admitted with the main diagnosis of symptomatic carotid disease. The admission rate of symptomatic patients was less than expected in the more affluent group (Carstair 1, p < 0.005) and significantly higher in the most deprived group (Carstair 7, p < 0.001). In comparison 192 patients underwent CEA. There were no differences between the expected and actual rates of CEA in each CDS, but the rates tended to be higher in the most affluent group. Geographical variation was also demonstrated with an increased rate of CEA in those patients living in the cities and a reduced rate in those in the rural communities.

CONCLUSION

patients from deprived socio-economic groups had a higher rate of symptomatic carotid disease, but this was not matched by an increased rate of CEA. This suggests that socio-economic inequalities in the prevalence of symptomatic carotid artery disease and treatment exist.

摘要

目的

近期证据表明社会经济地位与动脉粥样硬化之间存在密切关联。然而,关于社会经济地位、有症状的颈动脉疾病以及颈动脉内膜切除术(CEA)发生率之间的关系,相关信息较少。本研究旨在评估(1)因有症状的颈动脉疾病入院患者以及(2)在一个卫生保健区域接受CEA治疗患者的卡斯泰尔剥夺评分(CDS)。

方法

CDS评分根据1995年4月1日至2000年3月31日期间所有因短暂性脑缺血发作(TIA)或脑梗死所致中风(国际疾病分类第九版编码433.1、433.09、435、437.1;国际疾病分类第十版:I65.2、I63、I63.2、G45.1、G45.3、G45.9)入院患者的邮政编码确定。通过直接和间接标准化方法,考虑年龄和性别因素,确定每个CDS等级(1至7)的预期发生率和实际发生率。对接受颈动脉内膜切除术的患者进行了类似分析。结果采用曼特尔 - 亨泽尔检验进行分析。仅纳入首次入院患者和CEA手术病例。

结果

1203例患者因有症状的颈动脉疾病为主诊断入院。在较富裕组(卡斯泰尔1组,p < 0.005),有症状患者的入院率低于预期,而在最贫困组(卡斯泰尔7组,p < 0.001)则显著高于预期。相比之下,192例患者接受了CEA手术。每个CDS等级中CEA的预期发生率和实际发生率之间没有差异,但在最富裕组中发生率往往更高。还显示出地理差异,城市地区患者的CEA发生率较高,农村社区患者的发生率较低。

结论

来自社会经济贫困群体的患者有症状的颈动脉疾病发生率较高,但CEA发生率并未相应增加。这表明在有症状的颈动脉疾病患病率和治疗方面存在社会经济不平等现象。

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