Gibbs R G, Todd J C, Irvine C, Lawrenson R, Newson R, Greenhalgh R M, Davies A H
Department of Surgery, Charing Cross and Westminster Medical School, London.
Eur J Vasc Endovasc Surg. 1998 Jul;16(1):47-52. doi: 10.1016/s1078-5884(98)80091-9.
To examine the relationship between the incidence of transient ischaemic attack (TIA) and stroke on a national and regional level and the rate of carotid endarterectomy (CEA).
Patients entered onto a national primary care computerised database with a new diagnostic code of stroke or TIA between 1992 and 1995.
Analysis of data from the primary care database and routine data sources. Main outcome measures were incidence of TIA and stroke and rates of CEA.
The mean incidence per 100,000 of the population was 292 (TIA) and 356 (stroke) in England, 391 and 497 in Scotland and 349 and 448 in Northern Ireland. There was a variation in the incidence of TIA and stroke between both the regions and the regions and countries which was significant. There was a national increase in the rate of CEA between 1990 and 1995 which showed a marked variation across the regions. The inter-regional variation in rate of CEA correlated with the inter-regional difference in incidence of disease.
The incidence of TIA and stroke may be higher than previously recognised, and varies significantly between the regions. This is generally associated with the variation in performance of CEA.
在国家和地区层面研究短暂性脑缺血发作（TIA）和中风的发病率与颈动脉内膜切除术（CEA）的比率之间的关系。
1992年至1995年间被录入国家基层医疗计算机数据库且有新的中风或TIA诊断代码的患者。
对基层医疗数据库和常规数据源的数据进行分析。主要观察指标为TIA和中风的发病率以及CEA的比率。
在英格兰，每10万人中的平均发病率为TIA 292例、中风356例；在苏格兰为391例和497例；在北爱尔兰为349例和448例。TIA和中风的发病率在各地区之间以及地区与国家之间均存在显著差异。1990年至1995年间，全国CEA比率有所上升，且各地区间差异显著。CEA比率的地区间差异与疾病发病率的地区间差异相关。
TIA和中风的发病率可能高于此前的认知，且地区间差异显著。这通常与CEA实施情况的差异有关。
