School of Health and Related Research, University of Sheffield, Sheffield, South Yorkshire, UK.
Department of Landscape Architecture, University of Sheffield, Sheffield, South Yorkshire, UK.
BJS Open. 2023 Jul 10;7(4). doi: 10.1093/bjsopen/zrad056.
Carotid artery disease and stroke are more prevalent in socioeconomically deprived areas. The aim was to investigate socioeconomic disparities in carotid artery disease surgery rates and in outcomes following surgery.
The study used population-based ecological and cohort study designs, 31 672 census areas in England, hospital admissions from April 2006 to March 2018, the Index of Multiple Deprivation 2010 as the area-level deprivation indicator, and Poisson, logistic, and Cox regression.
A total of 54 377 patients (67 per cent men) from a population aged 55 years and older of 14.7 million had carotid artery disease procedures (95 per cent carotid endarterectomy). Carotid endarterectomy rates were 116 per cent (95% c.i. 101 to 132) higher in men and 180 per cent (95% c.i. 155 to 207) higher in women aged 55-64 years in the most compared with the least socioeconomically deprived areas by quintile. However, this difference diminished and appeared to reverse with increasing age, with 24 per cent (95% c.i. 14 to 33) and 12 per cent (95% c.i. -3 to 24) lower carotid endarterectomy rates respectively in men and women aged 85 years and older in the most deprived areas. Patients in deprived areas having carotid endarterectomy were more likely to have been admitted as symptomatic emergency carotid artery disease admissions. Mortality, and a combined outcome of mortality or stroke-related re-admission, were both worse in patients living in more deprived areas and were only partially accounted for by the higher prevalence of co-morbidities. There was, however, no clear pattern of association between deprivation and elective waiting time for carotid endarterectomy.
These results provide evidence of socioeconomic disparities in surgery for carotid artery disease. Clear policies are needed to address these disparities.
颈动脉疾病和中风在社会经济贫困地区更为普遍。本研究旨在调查颈动脉疾病手术率和手术后结果的社会经济差异。
本研究采用基于人群的生态和队列研究设计,以英格兰的 31672 个普查区、2006 年 4 月至 2018 年 3 月的住院数据、2010 年多维度贫困指数作为地区贫困指标,并采用泊松回归、逻辑回归和 Cox 回归进行分析。
共有 1470 万 55 岁及以上人群的 54377 例(67%为男性)患者进行了颈动脉疾病手术(95%为颈动脉内膜切除术)。与最贫困的五分位地区相比,男性在 55-64 岁的年龄组中,颈动脉内膜切除术的比例高 116%(95%可信区间 101-132),女性高 180%(95%可信区间 155-207)。然而,这种差异随着年龄的增长而缩小,并且似乎在逆转,在最贫困地区,85 岁及以上的男性和女性颈动脉内膜切除术的比例分别低 24%(95%可信区间 14-33)和 12%(95%可信区间 -3-24)。在最贫困地区接受颈动脉内膜切除术的患者更有可能因症状性紧急颈动脉疾病入院。生活在贫困地区的患者死亡率以及死亡率或中风相关再入院的综合结果均较差,这在一定程度上是由于合并症的患病率较高所致。然而,在颈动脉内膜切除术的选择性等待时间与贫困程度之间并没有明显的关联模式。
这些结果提供了颈动脉疾病手术存在社会经济差异的证据。需要制定明确的政策来解决这些差异。