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史蒂文斯-约翰逊综合征中的自体及异体羊膜移植术

Autologous allogeneic amniotic membrane grafting in Stevens-Johnson syndrome.

作者信息

Park Eun-Ha, Korn Tommy S, Vasani Sunil N, Kikkawa Don O

机构信息

Division of Ophthalmic Plastic and Reconstructive Surgery, UCSD Department of Ophthalmology, La Jolla, California 92093-0946, USA.

出版信息

Ophthalmic Plast Reconstr Surg. 2003 May;19(3):250-1. doi: 10.1097/01.iop.0000066652.91232.39.

Abstract

We describe the use of autologous allogeneic amniotic membrane in ocular surface reconstruction. A 28-year-old woman with cicatricial entropion from Stevens-Johnson syndrome had recurrent keratinization of the tarsal conjunctiva. Amniotic membrane from the patient's own conceptus was stored and successfully used in ocular surface reconstruction with improvement of ocular symptoms. Disease transmission is an important risk inherent in all human tissue transplantation. Use of carefully prepared autologous allogeneic amniotic membrane grafts should be considered in pregnant patients in need of ocular surface reconstruction.

摘要

我们描述了自体/异体羊膜在眼表重建中的应用。一名患有史蒂文斯-约翰逊综合征所致瘢痕性睑内翻的28岁女性,睑结膜反复角化。患者自身胚胎的羊膜被保存下来,并成功用于眼表重建,眼部症状得到改善。疾病传播是所有人体组织移植固有的重要风险。对于需要进行眼表重建的孕妇,应考虑使用精心制备的自体/异体羊膜移植物。

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