Lebovitz Harold E
Department of Medicine, State University of New York Health Science Center at Brooklyn, USA.
Psychiatr Q. 2003 Fall;74(3):277-90. doi: 10.1023/a:1024170622266.
Atypical antipsychotic drugs have become the treatment of choice for psychotic disorders. However, these medications, though certainly superior in many respects to the more traditional medications, have been shown to have a number of untoward consequences. Understanding of the metabolic consequences of these medications is essential for the psychiatrist. The possible development of diabetes, weight gain, and hypertriglyceridemia in patients taking atypical antipsychotics makes it imperative that the prescribing physician regularly monitor patients on these agents. One possible monitoring scheme is outlined and recommendations for treatment are discussed.
非典型抗精神病药物已成为治疗精神障碍的首选药物。然而,这些药物虽然在许多方面肯定优于传统药物,但已被证明有许多不良后果。精神科医生必须了解这些药物的代谢后果。服用非典型抗精神病药物的患者可能会出现糖尿病、体重增加和高甘油三酯血症,这使得开处方的医生必须定期监测服用这些药物的患者。本文概述了一种可能的监测方案,并讨论了治疗建议。