Woolsey Jeffrey, Miller Nicole, Theodorescu Dan
Department of Urology, University of Virginia Health Sciences Center, Box 422, Charlottesville, VA 22908, USA.
World J Urol. 2003 Sep;21(4):209-19. doi: 10.1007/s00345-003-0357-9. Epub 2003 Aug 13.
Prostate brachytherapy with permanent radioactive implants is becoming an increasingly popular treatment choice for patients with prostate cancer. This therapy is attractive to patients due to the fact that it is an outpatient procedure and in many cases has been associated with lower long-term risks of urinary incontinence and erectile dysfunction when compared to other curative modalities. This review will describe the history, isotopes used, implantation techniques, and results achieved with modern prostate brachytherapy. Results will be discussed both in terms of cancer control and health-related quality of life endpoints.
永久性放射性粒子植入前列腺近距离放射治疗正日益成为前列腺癌患者越来越受欢迎的治疗选择。这种治疗方法对患者具有吸引力,因为它是一种门诊手术,而且在许多情况下,与其他根治性治疗方式相比,其长期尿失禁和勃起功能障碍的风险较低。本综述将描述现代前列腺近距离放射治疗的历史、所用同位素、植入技术以及取得的结果。将从癌症控制和与健康相关的生活质量终点两个方面讨论结果。