Conze J, Krones C J, Prescher A, Schumpelick V
Chirurgische Klinik und Poliklinik, Rheinisch Westfälischen Technischen Hochshule, Aachen.
Dtsch Med Wochenschr. 2003 Aug 15;128(33):1706-8. doi: 10.1055/s-2003-41337.
A 21-year-old woman presented with predominantly right-sided cramp-like abdominal pain which had started the previous day. The abdomen was soft on palpation, the peristaltic sounds increased. Body temperature was normal.
Routine laboratory tests were unremarkable, including white cell count (4.5 G/l). and C-reactive protein.
She was admitted to hospital for observation. Because the symptoms persisted she underwent a right lower laparotomy because acute appendicitis was suspected. Intraperitoneal examination of the intestines revealed a soft, sponge-like foreign body just above the ileocecal valve. The overlying ileum was incised and a sponge removed. Postoperatively the patient reported having taken 4 capsules of CM3, a weight-reducing preparation, about 14 days ago. These capsules dissolve in the stomach and each releases a small sponge which expands and mechanically induces a feeling of satiation. The further course was unremarkable and she was discharged on the 8th postoperative day.
When producing weight-reducing preparations that act according to physico-mechanical principles, anatomical circumstances should be considered, and they should only be taken under medical supervision.
一名21岁女性,主要表现为右侧腹部绞痛样疼痛,始于前一天。触诊时腹部柔软,肠鸣音增强。体温正常。
常规实验室检查无异常,包括白细胞计数(4.5×10⁹/L)及C反应蛋白。
她入院观察。由于症状持续存在,因怀疑急性阑尾炎而接受了右下腹剖腹手术。对腹腔内肠道检查发现,在回盲瓣上方有一个柔软的、海绵样异物。切开覆盖其上的回肠并取出一块海绵。术后患者报告约14天前服用了4粒CM3胶囊,一种减肥制剂。这些胶囊在胃中溶解,每粒释放出一块小海绵,海绵膨胀并机械性地产生饱腹感。后续病程顺利,术后第8天出院。
在生产基于物理 - 机械原理起作用的减肥制剂时,应考虑解剖学情况,且只能在医学监督下服用。