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来自同一肾脏供体的肾移植:糖尿病患者和非糖尿病患者的结局

Renal transplantations from the same kidney donor: outcome of diabetic and non-diabetic patients.

作者信息

Reissell E, Lindgren L, Tikkanen I, Ahonen J

机构信息

Department of Anaesthesia, Helsinki University Central Hospital, Finland.

出版信息

Scand J Urol Nephrol. 1992;26(4):403-8. doi: 10.3109/00365599209181234.

Abstract

Diabetic (DM) nephropathy is an indication of renal transplantation in 30% of all cases in our hospital. We assessed retrospectively the outcome of these diabetics (DM) in comparison with their non-diabetic (NDM) controls. Each diabetic (n = 24) had a control (n = 24) receiving a kidney from the same donor. There was no difference in the stage of uraemia preoperatively. Anaesthesia and fluid therapy were standardized. Peroperative hypotension occurred more often in diabetics (NS). All operating parameters including cold ischaemia were comparable. Kidney function started immediately in 14/24 in the DM group and 13/24 in the NDM group and was delayed in 10/24 and 11/24, respectively. One diabetic patient rejected the transplant as did two non-diabetic patients. Postoperatively diuretics could be discontinued more often in the DM than in the NDM group (p < 0.05). Antihypertensives had to be started in the NDM more often (NS) than in the DM group. In conclusion, the outcome of diabetic patients after renal transplantation was comparable to their NDM controls.

摘要

在我院所有病例中,糖尿病(DM)肾病是30%肾移植病例的指征。我们回顾性评估了这些糖尿病患者(DM)与非糖尿病(NDM)对照者的结局。每名糖尿病患者(n = 24)均有一名来自同一供体肾脏的对照者(n = 24)。术前尿毒症分期无差异。麻醉和液体治疗标准化。术中低血压在糖尿病患者中更常见(无统计学意义)。所有手术参数包括冷缺血时间均具有可比性。DM组24例中有14例、NDM组24例中有13例肾功能立即恢复,分别有10例和11例延迟恢复。1例糖尿病患者和2例非糖尿病患者移植肾发生排斥反应。术后,DM组比NDM组更常能停用利尿剂(p < 0.05)。NDM组比DM组更常需要开始使用抗高血压药物(无统计学意义)。总之,糖尿病患者肾移植后的结局与NDM对照者相当。

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