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[胰岛素依赖型糖尿病终末期肾功能不全患者的持续非卧床腹膜透析及肾移植方案]

[Program of continuous ambulatory peritoneal dialysis and renal transplantation in insulin-dependent diabetics in the terminal stage of renal insufficiency].

作者信息

Mousson C, Tanter Y, Chalopin J M, Rifle G

机构信息

Département de Néphrologie et Réanimation Métabolique, Hôpital du Bocage, Centre Hospitalier Universitaire, Dijon.

出版信息

Nephrologie. 1987;8(4):205-9.

PMID:3320798
Abstract

A program of continuous ambulatory peritoneal dialysis (CAPD)-renal transplantation was set up on less than 55 years old insulin dependent diabetics with end stage renal failure. Ten patients were included (age range: 9-45 years, mean: 35.6). All these patients had many complications: retinopathy, arteritis, ischemic heart disease, hypertension, neuropathy, cutaneous infection. One patient refused CAPD and was hemodialyzed for 8 months before grafting. Nine patients were treated for 3 to 45 months (mean: 14.8). During CAPD therapy, better control of hypertension and blood glucose levels were achieved. Five patients received a cadaver renal transplant 3 to 27 months (mean: 13.3) after starting CAPD. All these transplants are functioning 12 to 62 months after grafting (mean: 26.4). No post-operative complications can be directly related to CAPD. No vascular complications occurred during post-transplant follow-up. So, an integrated program CAPD-renal transplantation could be of value for young insulin-dependent diabetics.

摘要

针对年龄小于55岁的胰岛素依赖型终末期肾衰竭糖尿病患者,制定了持续非卧床腹膜透析(CAPD)-肾移植计划。纳入了10例患者(年龄范围:9至45岁,平均35.6岁)。所有这些患者都有许多并发症:视网膜病变、动脉炎、缺血性心脏病、高血压、神经病变、皮肤感染。1例患者拒绝CAPD,在移植前接受了8个月的血液透析。9例患者接受了3至45个月的治疗(平均14.8个月)。在CAPD治疗期间,高血压和血糖水平得到了更好的控制。5例患者在开始CAPD治疗3至27个月(平均13.3个月)后接受了尸体肾移植。所有这些移植肾在移植后12至62个月(平均26.4个月)均功能良好。没有术后并发症可直接归因于CAPD。移植后随访期间未发生血管并发症。因此,CAPD-肾移植综合计划可能对年轻的胰岛素依赖型糖尿病患者有价值。

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